Hi;
As you would guess, that file is related to the USB ports/devices on the
system. Technical name is "USB Miniport Driver for Input Devices"
First thing I'd try is to re-install the drivers for any USB devices you
have on those systems. You might also try replacing that file
(hidusb.sys) with a known-good copy from a working 2000 computer or the
CD.
You might also need to re-install any ASUS chipset drivers (4-n-1, etc.)
that pertain to that motherboard.
Here's a page with some other USB troubleshooting ideas:
http://support.microsoft.com/default.aspx?scid=kb;en-us;242062

Signature
...Sky
Tom "Sky" King
=============
> Hi,
> I just installed Service Pack 4 on two Windows 2000 machines and
[quoted text clipped - 5 lines]
> Thanks,
> Felix Arends